Kinesins Lead Aging Microtubules to Catastrophe

نویسندگان

  • Anna Akhmanova
  • Marileen Dogterom
چکیده

The ability of growing microtubules to undergo catastrophes--abrupt switches from growth to shortening--is one of the key aspects of microtubule dynamics important for shaping cellular microtubule arrays. Gardner et al. show that catastrophes occur at a microtubule age-dependent rate and that depolymerizing kinesins can affect this process in fundamentally different ways.

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عنوان ژورنال:
  • Cell

دوره 147  شماره 

صفحات  -

تاریخ انتشار 2011